Folic acid effects blood arsenic metabolites
نویسندگان
چکیده
منابع مشابه
Highlight #1: Folic Acid Supplementation Lowers Blood Arsenic by Increasing as Methylation (manuscript in Preparation)
Chronic arsenic (As) exposure currently affects more than 100 million people worldwide. Methylation of ingested inorganic arsenic (InAs) to methylarsonic(MMA) and dimethylarsinic acids (DMA) relies on folate-dependent one carbon metabolism. In a recent, randomized, controlled trial, we analyzed total As and As metabolites in urine and showed that folic acid supplementation resulted in an increa...
متن کاملrole of folic acid on symptoms of chronic arsenic toxicity
background: chronic arsenic toxicity (arsenicosis) due to drinking of arsenic contaminated ground water is a global problem. however, its treatment is unsatisfactory. methylation of arsenic facilitates its urinary excretion. persons with relatively lower proportion of urinary dimethyl arsenic acid (dma) are found to have at greater risk of developing symptoms of arsenicosis including its compli...
متن کاملEffects of a folic acid antagonist on nucleic acid metabolism.
Microbiological evidence (1) first implicated folic acid in nucleic acid synthesis, and several lines of investigation suggest that citrovorum factor, or another derivative of folic acid, may function in some manner as a coenzyme in the metabolism of a l-carbon moiety. The function of the formy1 group in rhizopterin (2) and citrovorum factor (3) has not been clarified. The incorporation of form...
متن کاملFolic Acid
Introduction Folic acid, also known generically as folate or folacin, is a member of the B-complex family of vitamins, and works in concert with vitamin B12. Folic acid functions primarily as a methyl-group donor involved in many important body processes, including DNA synthesis. Therapeutically, folic acid is instrumental in reducing homocysteine levels and the occurrence of neural tube defect...
متن کاملMicrobiologic determination of folic acid derivatives in blood.
By NATHAN GRossowlcz, Fu amnn MANDELBAUM-SHAVIT, Rosy DAVIDOFF AND J. ARONOVITCH F OLIC ACID (F.A. ) deficiency in man may be due to a variety of factors. The most important ones are considered to be unusually poor diets, faulty absorption of the vitamin from the intestinal tract, derangement in the intestinal flora resulting in low synthesis of the vitamin and faulty metabolism of the vitamin ...
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ژورنال
عنوان ژورنال: Environmental Epidemiology
سال: 2019
ISSN: 2474-7882
DOI: 10.1097/01.ee9.0000606056.51832.73